Hif1a genecard
WebOMIM, HGNC, Ensembl, GeneCard, Gene: Protein: hypoxia-inducible factor 1-alpha: Source: NCBI Accessed: 31 August, 2024: Ontology: What does this gene/protein do? Show (96) Pathways: What pathways are ... HIF1A driven transcriptional response in hypoxia depends on epigenetic control at DNA methylation status of gene regulatory regions. WebSupplementary Table 1:Pathogenic targets of HIE from DisGeNET,Drugbank and Genecard databases Gene Gene Gene Gene Gene Gene Gene Gene Gene Gene Gene NOS2 …
Hif1a genecard
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Web21 de mar. de 2024 · Entrez Gene Summary for HNF1A Gene. The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. … Web20 de jun. de 2024 · In this review, we will discuss the current understandings of hypoxia signaling in human diseases by the organ systems, including the heart, lung, liver, and kidney. We will also discuss the ...
Web17 de ago. de 2024 · Mutational inactivation of VHL is the earliest genetic event in the majority of clear cell renal cell carcinomas (ccRCC), leading to accumulation of the HIF-1α and HIF-2α transcription factors. While correlative studies of human ccRCC and functional studies using human ccRCC cell lines have implicated HIF-1α as an inhibitor and HIF-2α … WebScienceDirect.com Science, health and medical journals, full text ...
Web9 de dez. de 2024 · Blood-borne metastasis to the brain is a major complication of breast cancer, but cellular pathways that enable cancer cells to selectively grow in the brain microenvironment are poorly understood. WebBlocking the targeting of Parg by miR-383 prevented the protective effect of Hif1a deletion in macrophages on atherosclerosis and necrotic core formation in mice. Conclusions: Our findings unveil a new mechanism by which activation of HIF-1α in inflammatory macrophages increases necroptosis through microRNA-mediated ATP depletion, thus …
WebPolyclonal Antibody for studying HIF1A. Cited in 194 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, HIF-1α Antibody (CST #3716) is ready to ship.
Web19 de jul. de 2024 · HIF1A-AS3 HIF1A antisense RNA 3 [ (human)] Gene ID: 105370526, updated on 19-Jul-2024. Summary. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. HIF1A-AS3 HIF1A antisense RNA 3 [ (human)] Gene ID: 105370526, updated on ... bittles hurt funeral home greencastlehttp://html.rhhz.net/SWJSTB/html/2016-8-8.htm bittles surnameWeb21 de mar. de 2024 · HIF3A (Hypoxia Inducible Factor 3 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF3A include Erythrocytosis, Familial, 4 and … dataverse group teamsWebHypoxia-inducible protein 2 (HIG2) has been implicated in canonical Wnt signaling, both as target and activator. The potential link between hypoxia and an oncogenic signaling pathway might play a pivotal role in renal clear-cell carcinoma characterized by constitutive activation of hypoxia-inducible factors (HIFs), and hence prompted us to analyze HIG2 regulation … bittles eyewearWeb25 de jun. de 2015 · Xihua Chen, Jianbing Liu, Bin He, Yunfeng Li, Shuyan Liu, Bin Wu, Shufang Wang, Shucheng Zhang, Xiangbo Xu, Jiedong Wang, Vascular endothelial growth factor (VEGF) regulation by hypoxia inducible factor-1 alpha (HIF1A) starts and peaks during endometrial breakdown, not repair, in a mouse menstrual-like model, Human … bittles hurt funeral home obitsWebHypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong correlation between … bittles hurt funeral homeWeb1 de set. de 2024 · Co-transfection of HEK293FT cells with HIF1A-sh-GFP and HIF1α-P2A-RFP plasmids validated the successful shRNA knockdown of HIF1A mRNA by the expression of RFP and GFP reporters, as the HIF1α-P2A-RFP plasmid allows for HIF1α and RFP to be expressed as a single mRNA transcript which is then translated as two … dataverse high availability