WebMay 17, 2024 · The optopatcher was used to identify MSNs of the direct and indirect pathways in real time during recordings using focal optogenetic stimulation through the patch pipette. Our results show that the laterality of sensory input in the striatum is encoded in a pathway-dependent manner and requires dopaminergic input. Thus, our study … WebOct 17, 2013 · This device, which we called “optopatcher” allows whole cell patch-clamp recording simultaneously with direct projection of light from the recording pipette. The …

In-vivo optogenetics and pharmacology in deep intracellular recordings

WebThe Optopatcher provides unmatched accuracy in applying optical stimulation to an in-vivo patch-clamp protocol, integrating the fiber optic within the same microelectrode being … WebOptoPatcher. Apply optical stimulation through patch clamp pipettes; Can be used with pipettes from 1.2 mm to 2 mm OD; Available for Axon, Heka, npi and other amplifiers; … csi rainy multispeciality hospital

Opthopatch Eye patches that bring a smile to your face!

WebHere we used the optopatcher in vivo to record the membrane potential of neurons from different cortical layers in the motor cortex of transgenic mice expressing channelrhodopsin-2 under the Thy1 promoter. We demonstrate the utility of the optopatcher by recording LFP and intracellular responses to light stimulation. WebFiber Optic Cannula for Optopatcher. The fiber optic cannula for Optopatcher models are assembled at A-M Systems and come in lengths of 75 mm, 100 mm and 150 mm. Nasal Cannula. Nasal Cannula have non-flare nasal prongs, and are available in regular or crush-resistant tubing. All tubing is made of soft vinyl for patient comfort. WebThe Optopatcher® provides unmatched accuracy in applying optical stimulation to an in-vivo patch-clamp protocol. The holder houses both an optical fiber and an electrode enabling … c s i rainy multi speciality hospital