Solubility of gemcitabine hydrochloride

WebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … WebSolubility: Soluble in DMSO at 12.5 mg/mL with slight warming; very poorly soluble in ethanol; soluble in water at 25 mg/mL with slight warming; buffers, ... Gemcitabine …

Gemcitabine hydrochloride (CAS 122111-03-9): R&D …

WebMar 1, 2024 · One vial contains Gemcitabine hydrochloride equivalent to 200 mg Gemcitabine One vial contains Gemcitabine hydrochloride equivalent to 1000 mg Gemcitabine . After reconstitution, the solution contains 38 mg/ml of Gemcitabine. Excipients: Each 200 mg vial contains 3.5 mg (<1 mmol) sodium. Each 1,000 mg vial … WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used antineoplastic agent and antimetabolite; Gemcitabine is a widely used antitumor agents in both clinics and research labs; can i put stuff inside pc case https://politeiaglobal.com

Gemcitabine Hydrochloride - NCI - National Cancer Institute

WebGemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. … WebNov 25, 2024 · The empirical formula for gemcitabine HCl is C 9 H 11 F 2 N 3 O 4 • HCl. It has a molecular weight of 299.66. Gemcitabine HCl is soluble in water, slightly soluble in … WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … can i put sunscreen on my hair

Gemcitabine hydrochloride = 98 HPLC 122111-03-9 - Sigma-Aldrich

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Solubility of gemcitabine hydrochloride

Gemcitabine hydrochloride = 98 HPLC 122111-03-9 - Sigma-Aldrich

WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); &gt;= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … WebGemcitabine Hydrochloride, CAS: 122111-03-9, is a deoxycytidine analog that inhibits ribonucleotide reductase &amp; induces apoptosis. ... Gemcitabine Hydrochloride, sc-204763, …

Solubility of gemcitabine hydrochloride

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WebGemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a … WebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to …

WebApplication. It is intended to be used as a USP reference standard in specified quality tests and assays. Also used to prepare standard solutions in the assay and impurities analysis … WebGemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. …

WebApr 1, 1999 · Gemcitabine is a fluoro-cytidine analog with primarily antitumor activity and is administered intravenously [120]. Although its hydrochloride salt is well soluble in water … WebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67].

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WebGemcitabine, HCl - CAS 122111-03-9 - Calbiochem. View Price and Availability. Supelco. PHR2582. Gemcitabine hydrochloride. Pharmaceutical Secondary Standard; Certified … can i put synthetic oil in my old carWebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, … five letter word ending in tchWebGemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate ... five letter word ending in uctWebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored … five letter word ending in umphWebJun 29, 2024 · Gemcitabine 1 g/m 2 (as 30-minute infusion) has been given on days 1 and 8 of each 21-day cycle; administered in combination with cisplatin (25 mg/m 2 as 1-hour … five letter word ending in shWebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... five letter word ending in untWebTest conditions included (1) reconstituted gemcitabine at a concentration of 38 mg/mL as the hydrochloride salt in 0.9% sodium chloride or sterile water for injection in the original … five letter word ending in tar